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William Henry Holmes was born in 1795 at South Carolina, USA.1,3,5,6,7 He married Margaret Ramey Green circa 1823 at Charleston County, South Carolina, USA.4 William Henry Holmes lived in 1850; St Michael and St Phillip, Charleston, South Carolina.1 He lived in 1860; Charleston Ward 5, Charleston, South Carolina, United States.7 He lived in 1870; Charleston, Charleston, South Carolina, United States.5 He died on 16 March 1874 at Charleston County, South Carolina, USA.3,6