Ruthless venture capitalist "Jack" Watson conspires to steal or sabotage BioGen's cultures of Frank's cells. As part of his terms for financing BioGen, Watson previously forced the company to accept his irresponsible nephew Brad Gordon as its security chief. After Brad's carelessness nearly allows one of Watson's sabotage attempts to succeed, the company takes advantage of his attraction to teenage girls, and engineers his being accused and convicted of raping a minor. Watson's price for providing a defense lawyer is that Brad must contaminate BioGen's cultures. Brad's lawyer plans to claim in defense that Brad has a gene for recklessness and instructs him to engage in various high-risk activities. As a result, Brad gets into a fight with a pair of martial arts experts and is finally shot by the police.
After Brad's sabotage, BioGen consults lawyers, who advise that under United States law they have the rights to all of Frank's cell line and thus the right to extract replacement cells, by force if necessary, from Frank or any of his descendants. When Frank goes on the run, BioGen hires bounty hunter Vasco Borden to obtain such cells, regardless of whether the donors consent. Vasco plans to snatch Frank's grandson Jamie from his school but is foiled by Jamie's mother Alex, whom he tries to seize instead. After escaping, Alex and Jamie also go on the run.
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